Nasal allergen challenge
نویسندگان
چکیده
منابع مشابه
Omalizumab inhibits allergen challenge-induced nasal response.
Elevated serum levels of antigen-specific immunoglobulin (Ig)E are often associated with allergic respiratory diseases. This parallel-group, randomised, double-blind, placebo-controlled trial was designed to study the influence of omalizumab on the early nasal response to allergen challenge reflected by symptom score and inflammatory marker levels in nasal lavage fluid (NAL). A total of 23 pati...
متن کاملNasal nitric oxide measurements in the assessment of nasal allergen challenge.
BACKGROUND Several objective methods are used to assess the result of nasal allergen challenge. OBJECTIVE The aim of this study was to compare the diagnostic value of nasal nitric oxide (nNO) measurements with that of peak nasal inspiratory flow (PNIF), nasal lavage fluid beta-tryptase levels, and changes in cell count after nasal challenge with grass pollen. METHODS The study population co...
متن کاملthe safety of nasal allergen challenge test assessed in lower airways
the aim of the study was to assess the safety of nasal allergen challenge, and the use of certain parameters applied in assessing the condition of the respiratory system. we enrolled 30 patients diagnosed with allergy to common environmental allergens and 30 healthy controls. the safety of nasal challenge tests with an allergen was assessed by measuring the concentration of exhaled nitric oxide...
متن کاملThe release of IL-31 and IL-13 after nasal allergen challenge and their relation to nasal symptoms
UNLABELLED BACKGROUND IL-31, a recently discovered member of the gp130/IL-6 cytokine family, is mainly expressed by human mast cells and T helper type 2 cells. IL-31 is a key trigger of atopic dermatitis. Recent studies also suggest a role of IL-31 in the pathogenesis of other allergic diseases including allergic rhinitis. In the present study we studied the release of IL-31 and IL-13 in all...
متن کاملEosinophil recruitment to nasal nerves after allergen challenge in allergic rhinitis.
In allergen challenged animal models, eosinophils localize to airway nerves leading to vagally-mediated hyperreactivity. We hypothesized that in allergic rhinitis eosinophils recruited to nasal nerves resulted in neural hyperreactivity. Patients with persistent allergic rhinitis (n=12), seasonal allergic rhinitis (n=7) and controls (n=10) were studied. Inferior nasal turbinate biopsies were obt...
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ژورنال
عنوان ژورنال: Alergologia Polska - Polish Journal of Allergology
سال: 2018
ISSN: 2353-3854
DOI: 10.5114/pja.2018.80738